Prone position & NMB in ARDS

Here are the slides from Cheau’s recent journal club presentation on prone position and neuromuscular blockade in ARDS. It’s an excellent review of two extensively investigated adjunctive interventions in ARDS management.

Seminal references for interested interlocutors:

ProSEVA trial

Comprehensive review of prone position in ARDS

The haemodynamic effects appear to depend on the initial preload reserve and the interaction of reduced RV afterload and increased LV afterload with biventricular function.

Haemodynamic effects of prone position

Prone position unloads the RV

The ROSE trial of early NMB in ARDS:

ROSE